Cat:pGMAD000512
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU
pGMAD000512
Categories adv, ADV plasmid, Gene Therapy, orf
Availability:3-7 business days
Description
Catalog ID
pGMAD000512
Gene Name
MED23
Product Name
Accession Number
NM_001270521.1
Gene ID
9439
Species
human
Product Type
Adenovirus plasmid
Insert Length
4080
Gene Alias
ARC130;CRSP130;CRSP133;CRSP3;DRIP130;MRT18;SUR-2;SUR2
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
Maker
GFP
Regulation
overexpression