Cat:pGMAD000544
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU
pGMAD000544
Categories adv, ADV plasmid, Gene Therapy, orf
Availability:3-7 business days
Description
Catalog ID
pGMAD000544
Gene Name
AXL
Product Name
Accession Number
NM_021913.5
Gene ID
558
Species
human
Product Type
Adenovirus plasmid
Insert Length
2685
Gene Alias
ARK;JTK11;Tyro7;UFO
Fluorescent Label
EGFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]
Maker
EGFP
Regulation
overexpression