Cat:pGMAD000556
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMAD000556
Gene Name
Sirt7
Product Name
Accession Number
NM_153056.3
Gene ID
209011
Species
house mouse
Product Type
Adenovirus plasmid
Insert Length
1209
Gene Alias
Enables NAD-dependent histone deacetylase activity (H3-K18 specific) and protein-propionyllysine depropionylase activity. Involved in several processes, including homologous chromosome pairing at meiosis; protein deacylation; and regulation of double-strand break repair via nonhomologous end joining. Located in chromatin and site of double-strand break. Is expressed in several structures, including 1st branchial arch maxillary component; central nervous system; eye; gonad; and spleen. Orthologous to human SIRT7 (sirtuin 7). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
Maker
GFP
Regulation
overexpression
