human EGFR Lentivirus plasmid
Cat:pGMLV000216
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000216
Gene Name
EGFR
Product Name
human EGFR Lentivirus plasmid
Accession Number
NM_005228.4
Gene ID
1956
Species
human
Product Type
Lentivirus plasmid
Insert Length
3633
Gene Alias
ERBB;ERBB1;HER1;mENA;NISBD2;PIG61
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
Maker
GFP+PURO
Regulation
overexpression
