Pre-made Fulranumab benchmark antibody ( Whole mAb, anti-NGFB/NGF therapeutic antibody, Anti-HSAN5 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Fulranumab biosimilar, Whole mAb, Anti-NGFB/NGF Antibody: Anti-HSAN5 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Fulranumab is a monoclonal antibody against nerve growth factor. It was designed for the treatment of pain.
| Products Name (INN Index) | Pre-Made Fulranumab biosimilar, Whole mAb, Anti-NGFB/NGF Antibody: Anti-HSAN5 therapeutic antibody |
|---|---|
| INN Name | Fulranumab |
| Target | NGF |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG2 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | 4m6o:HL |
| 95-98% SI Structure | None |
| Year Proposed | 2010 |
| Year Recommended | 2011 |
| Companies | Janssen Pharmaceuticals,Janssen Research & Development,Takeda,Amgen |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Pain,Back pain,Cancer pain,Musculoskeletal pain,Neuropathic pain |
| Development Tech | Abgenix XenoMouse |
| Previous Name | NA |
| Gm Offical Target Name | NGFB |
| Package |
