Pre-made Lemzoparlimab benchmark antibody ( Whole mAb, anti-CD47 therapeutic antibody, Anti-IAP/OA3/MER6 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Lemzoparlimab biosimilar, Whole mAb, Anti-CD47 Antibody: Anti-IAP/OA3/MER6 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Lemzoparlimab is a differentiated anti-CD47 monoclonal antibody designed to minimize inherent binding to normal red blood cells while preserving its strong anti-tumor activity. … “Lemzoparlimab has already shown promising and differentiated features as a novel therapy in phase 1 studies.
| Products Name (INN Index) | Pre-Made Lemzoparlimab biosimilar, Whole mAb, Anti-CD47 Antibody: Anti-IAP/OA3/MER6 therapeutic antibody |
|---|---|
| INN Name | Lemzoparlimab |
| Target | CD47 |
| Format | Whole mAb |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG4 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2020 |
| Year Recommended | NA |
| Companies | I-Mab Biopharma |
| Conditions Approved | NA |
| Conditions Active | Lymphoma,Solid tumours,Acute myeloid leukaemia,Myelodysplastic syndromes |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | CD47 |
| Package |
