Pre-made Miptenalimab benchmark antibody ( Whole mAb, anti-LAG3 therapeutic antibody, Anti-CD223 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Miptenalimab biosimilar, Whole mAb, Anti-LAG3 Antibody: Anti-CD223 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Miptenalimab (formerly BI 754111) is a humanised IgG4 anti-lymphocyte-activation gene 3 (LAG3) monoclonal antibody and an immune checkpoint inhibitor, being developed by Boehringer Ingelheim for the treatment of solid tumours, head and neck cancer and non-small cell lung cancer.
| Products Name (INN Index) | Pre-Made Miptenalimab biosimilar, Whole mAb, Anti-LAG3 Antibody: Anti-CD223 therapeutic antibody |
|---|---|
| INN Name | Miptenalimab |
| Target | LAG3 |
| Format | Whole mAb |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG4 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2019 |
| Year Recommended | 2020 |
| Companies | Boehringer Ingelheim |
| Conditions Approved | NA |
| Conditions Active | Solid tumours,Head and neck cancer,Non-small cell lung cancer |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | LAG3 |
| Package |
