rat Arl6ip1 AAV plasmid
Cat:pGMAAV000132
Availability:3-7 business days
Description
Catalog ID
pGMAAV000132
Gene Name
Arl6ip1
Product Name
rat Arl6ip1 AAV plasmid
Accession Number
NM_198737.2
Gene ID
293551
Species
rat
Product Type
AAV plasmid
Insert Length
612
Gene Alias
Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including endoplasmic reticulum tubular network organization; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and positive regulation of L-glutamate import across plasma membrane. Predicted to be located in cytosol and endoplasmic reticulum membrane. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be part of Sec61 translocon complex. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 61. Orthologous to human ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
Maker
Regulation
overexpression
