Author Archives: shanzhu

Protocol of CRISPR /Cas9 mediated gene knockout in vitro and in vivo

CRISPR/Cas9 protocol Download Gene editing, also called genome editing, is a group of technologies to change the sequence of DNA in the genome. Several approaches to genome editing have been developed, including Zinc Finger, TALEN, and CRISPR/Cas9. Compared with the other gene editing tools, CRISPR/Cas9 system is faster, cheaper, more accurate, and more efficient, showing […]

What is CRISPR/Cas9 delivery system

CRISPR/Cas9 protocol Download Gene editing, also called genome editing, is a group of technologies to change the sequence of DNA in the genome. Several approaches to genome editing have been developed, including Zinc Finger, TALEN, and CRISPR/Cas9. Compared with the other gene editing tools, CRISPR/Cas9 system is faster, cheaper, more accurate, and more efficient, showing […]

Top 35 treatments in development against Coronavirus disease 2019 (COVID-19)

AbbVie Treatment: Kaletra® (also marketed as Aluvia; lopinavir/ritonavir) Type: HIV-1 protease inhibitor indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and children 14 days old and older. Status: China’s National Health Commission authorized Kaletra to treat pneumonia caused by SARS-CoV-2, AbbVie announced on January 27. AbbVie has donated RMB 10 million ($1.4 […]

GeneMedi knowledge base of Coronavirus disease 2019 (COVID-19): A Collection of reviews, diagnosis protocols, and guidance

1. Introduction COVID-19, a novel pathogenic coronavirus (2019-nCoV or SARS-CoV2) induced disease, emerged in China and spread globally rapidly. GeneMedi produces kinds of recombinant 2019 nCoV(SARS2 coronavirus) antigens as shown below: Nucleocapsid(N protein), Spike(S protein), RBD, S1+S2 ECD, Envelope (E protein), 3C-like Proteinase. All the recombinant proteins of 2019 nCoV are suitable for in functional […]

Pre-made gene ORF plasmids for 2019 nCoV (SARS2 coronavirus, COVID-19) N protein,S protein(Spike),RBD,E protein(Envelope),M protein, ORF1ab/3a/6/7/8/10

Content index About Pre-made gene ORF plasmids for 2019 nCoV (SARS2 coronavirus, COVID-19) COVID-19, a novel pathogenic coronavirus (2019-nCoV or SARS-CoV2) induced disease, emerged in China and spread globally rapidly. GeneMedi offers pre-made gene ORF plasmids for 2019 nCoV (SARS2 coronavirus, COVID-19) as shown below: N protein(Nucleocapsid), S protein(Spike, full lenth), S1 protein(Spike), S protein […]

Recombinant 2019 nCoV(SARS2 coronavirus) Antigens reagents:Nucleocapsid(N protein), Spike(S protein), RBD, Mpro(Main protease, 3CLpro), Envelope (E protein), PLpro(Nsp3), RdRP(Nsp12), Nsp10, Nsp16, ACE2,Spike trimer Protein, Spike D614G/N501Y/B.1.1.7

Content index Introduction of GeneMedi’s COVID-19 Recombinant Antigens reagents COVID-19, a novel pathogenic coronavirus (2019-nCoV or SARS-CoV2) induced disease, emerged in China and spread globally rapidly. GeneMedi produces kinds of recombinant 2019 nCoV (SARS2 coronavirus) antigens as shown below: Nucleocapsid (N protein), Spike(S protein), RBD, S1+S2 ECD, Envelope (E protein), 3C-like Proteinase (also named Mpro, […]

An Insight of comparison between COVID-19 (2019-nCoV) and SARS-CoV in pathology and pathogenesis

Full-text Download Author:Xiaolong Cai1. Hanbio Research Center, Hanbio Tech Co. Ltd., Shanghai, P.R. China (www.hanbio.net)2. R&D Center, GeneMedi Co.Ltd., Shanghai, P.R. China (www.genemedi.com) Abstract:COVID-19, a novel pathogenic coronavirus emerged in China and spread globally rapidly. COVID-19 shares above 85% identity in genome with SARS-CoV. Patients infected by COVID-19 and SARS-CoV also reveal similar clinical characteristics. Here […]

Knowledge,research publication and gene information collection of 2019 Wuhan Novel coronavirus(2019-nCoV)

Interim Laboratory Guidance Version Download 2019 Wuhan Novel coronavirus, (2019-nCoV by WHO), is also known as Wuhan coronavirus, Wuhan seafood market pneumonia virus and Wuhan pneumonia, is a positive-sense, single-stranded RNA coronavirus first reported in 2019. The virus was genomically sequenced after nucleic acid testing on a positive patient sample in a patient with pneumonia during the 2019–2020 Wuhan pneumonia outbreak. On 20 January 2020, human-to-human transmission was confirmed […]

CAR-NK immunotherapy and cancer therapy

Lentivirus Protocol Download Cell therapy is a kind of medicine aiming to cure disease or alleviate disease symptoms via direct infusion or transplantation of cells, which can be autologous or allogeneic. With several decades’ development and optimization, immuno-oncology cells (such as T cells, nature killer cells, etc.), stem cells (embryonic stem cells, induced pluripotent stem […]

TCR-T immunotherapy and cancer therapy

Lentivirus Protocol Download Cell therapy is a kind of medicine aiming to cure disease or alleviate disease symptoms via direct infusion or transplantation of cells, which can be autologous or allogeneic. With several decades’ development and optimization, immuno-oncology cells (such as T cells, nature killer cells, etc.), stem cells (embryonic stem cells, induced pluripotent stem […]