Pre-made Apamistamab benchmark antibody ( Whole mAb Radiolabelled, anti-PTPRC therapeutic antibody, Anti-B220/CD45/CD45R/GP180/L-CA/LCA/LY5/T200 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Apamistamab biosimilar, Whole mAb Radiolabelled, Anti-PTPRC Antibody: Anti-B220/CD45/CD45R/GP180/L-CA/LCA/LY5/T200 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The investigational drug 131-I apamistamab is a protein combined with a radioactive form of iodine, which gives off a small amount of radiation. … It kills them, which prevents them from making other proteins associated with the side effects seen in some people who receive CAR T-cell therapy.
| Products Name (INN Index) | Pre-Made Apamistamab biosimilar, Whole mAb Radiolabelled, Anti-PTPRC Antibody: Anti-B220/CD45/CD45R/GP180/L-CA/LCA/LY5/T200 therapeutic antibody |
|---|---|
| INN Name | Apamistamab |
| Target | PTPRC |
| Format | Whole mAb Radiolabelled |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2018 |
| Year Recommended | 2019 |
| Companies | Actinium Pharmaceuticals,Fred Hutchinson Cancer Research Center |
| Conditions Approved | NA |
| Conditions Active | Acute myeloid leukaemia,Myelodysplastic syndromes,Precursor cell lymphoblastic leukaemia-lymphoma |
| Conditions Discontinued | Hodgkin's disease,Non-Hodgkin's lymphoma |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | PTPRC |
| Package |
