Pre-made Apamistamab benchmark antibody ( Whole mAb Radiolabelled, anti-PTPRC therapeutic antibody, Anti-B220/CD45/CD45R/GP180/L-CA/LCA/LY5/T200 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-029

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SKU GMP-Bios-ab-029 Category Tag

Product Details

Pre-Made Apamistamab biosimilar, Whole mAb Radiolabelled, Anti-PTPRC Antibody: Anti-B220/CD45/CD45R/GP180/L-CA/LCA/LY5/T200 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The investigational drug 131-I apamistamab is a protein combined with a radioactive form of iodine, which gives off a small amount of radiation. … It kills them, which prevents them from making other proteins associated with the side effects seen in some people who receive CAR T-cell therapy.

Products Name (INN Index)

Pre-Made Apamistamab biosimilar, Whole mAb Radiolabelled, Anti-PTPRC Antibody: Anti-B220/CD45/CD45R/GP180/L-CA/LCA/LY5/T200 therapeutic antibody

INN Name

Apamistamab

Target

PTPRC

Format

Whole mAb Radiolabelled

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-III

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2018

Companies

Actinium Pharmaceuticals,Fred Hutchinson Cancer Research Center

Conditions Approved

NA

Conditions Active

Acute myeloid leukaemia,Myelodysplastic syndromes,Precursor cell lymphoblastic leukaemia-lymphoma

Conditions Discontinued

Hodgkin's disease,Non-Hodgkin's lymphoma

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

PTPRC

Package

, ,

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