Pre-made Frunevetmab benchmark antibody ( Feline Whole mAb, anti-NGFB/NGF therapeutic antibody, Anti-HSAN5 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Frunevetmab biosimilar, Feline Whole mAb, Anti-NGFB/NGF Antibody: Anti-HSAN5 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Frunevetmab is a Felinized monoclonal antibody that can be potentially used in the treatment of Feline osteoarthritis (OA). It inhibits the activity of nerve growth factor (NGF), a mediator of pain signaling and nerve growth.
| Products Name (INN Index) | Pre-Made Frunevetmab biosimilar, Feline Whole mAb, Anti-NGFB/NGF Antibody: Anti-HSAN5 therapeutic antibody |
|---|---|
| INN Name | Frunevetmab |
| Target | NGF |
| Format | Feline Whole mAb |
| Derivation | Mouse |
| Species Reactivity | Feline |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Unknown |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2016 |
| Year Recommended | 2017 |
| Companies | Nexvet |
| Conditions Approved | NA |
| Conditions Active | Feline osteoarthritis |
| Conditions Discontinued | NA |
| Development Tech | PETization Technology |
| Previous Name | NA |
| Gm Offical Target Name | NGFB |
| Package |
