Pre-made Itepekimab benchmark antibody ( Whole mAb, anti-IL33 therapeutic antibody, Anti-C9orf26/DVS27/IL1F11/NF-HEV/NFEHEV Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Itepekimab biosimilar, Whole mAb, Anti-IL33 Antibody: Anti-C9orf26/DVS27/IL1F11/NF-HEV/NFEHEV therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Itepekimab is an anti-interleukin-33 (IL-33) monoclonal antibody being developed by Sanofi, in collaboration with Regeneron Pharmaceuticals, for the treatment.
| Products Name (INN Index) | Pre-Made Itepekimab biosimilar, Whole mAb, Anti-IL33 Antibody: Anti-C9orf26/DVS27/IL1F11/NF-HEV/NFEHEV therapeutic antibody |
|---|---|
| INN Name | Itepekimab |
| Target | IL33 |
| Format | Whole mAb |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG4 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2019 |
| Year Recommended | 2020 |
| Companies | Regeneron Pharmaceuticals,Sanofi |
| Conditions Approved | NA |
| Conditions Active | Chronic obstructive pulmonary disease |
| Conditions Discontinued | Allergic asthma,Inflammation,Asthma,Atopic dermatitis |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | IL33 |
| Package |
