Pre-made Panitumumab benchmark antibody ( Whole mAb, anti-EGFR therapeutic antibody, Anti-ERBB/ERRP/HER1/mENA/ERBB1/PIG61/NISBD2 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Panitumumab biosimilar, Whole mAb, Anti-EGFR Antibody: Anti-ERBB/ERRP/HER1/mENA/ERBB1/PIG61/NISBD2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).
| Products Name (INN Index) | Pre-Made Panitumumab biosimilar, Whole mAb, Anti-EGFR Antibody: Anti-ERBB/ERRP/HER1/mENA/ERBB1/PIG61/NISBD2 therapeutic antibody |
|---|---|
| INN Name | Panitumumab |
| Target | EGFR |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG2 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | Active |
| 100% SI Structure | 5sx5:HL:JK/5sx4:HL:JI |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2004 |
| Year Recommended | 2005 |
| Companies | Amgen,Grupo Espanol Multidisciplinario del Cancer Digestivo,Netherlands Cancer Institute,Novartis,Takeda,University of Texas M. D. Anderson Cancer Center,Wissenschaftlicher Service Pharma |
| Conditions Approved | Colorectal cancer |
| Conditions Active | Anal cancer,Bladder cancer,Breast cancer,Gastric cancer,Neuroendocrine tumours,Oesophageal cancer,Rectal cancer |
| Conditions Discontinued | Head and neck cancer,Malignant melanoma,Prostate cancer,Renal cell carcinoma,Solid tumours |
| Development Tech | Abgenix XenoMouse |
| Previous Name | NA |
| Gm Offical Target Name | EGFR |
| Package |
