Pre-Made Filgrastim Biosimilar, Recombinant Protein targeting CSF3R: Recombinant therapeutic protein targeting CD114/GCSFR/SCN7 for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Filgrastim Biosimilar, Recombinant Protein targeting CSF3R: Recombinant therapeutic protein targeting CD114/GCSFR/SCN7 is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Filgrastim is a recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog. Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from the bone marrow. Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. It has a number of therapeutic uses, including the management and prevention of infections and febrile neutropenia in patients receiving myelosuppressive chemotherapy or radiation therapy
| Products Name (INN Index) | Pre-Made Filgrastim Biosimilar, Recombinant Protein targeting CSF3R: Recombinant therapeutic protein targeting CD114/GCSFR/SCN7 |
|---|---|
| INN Name | filgrastim |
| Target | CSF3R |
| Format | Recombinant Protein |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF) |
| VD LC | CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF) |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Amgen (Thousand Oaks CA USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | CSF3R |
| Package |
