Category Archives: gene therapy article

Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre)

Content index Product list: Cre/loxP tools in AAV vector(AAV-Cre), adenoviral vector(Ad-Cre) and lentiviral vector(Lv-Cre) Abstract Cre-loxP system is widely used in the field of biosciences, especially in the generation of genetically engineered mice (knockout or overexpression), enabling researchers to study the function of gene of interest (GOI). To date, numerous systems, derived from the basic […]

Products & solutions & information collection of COVID-19 vaccines, new variants of SARS-CoV-2 and efficacy evaluation solutions

Table of Contents BACKGROUND Challenge of COVID-19 vaccine discovery & development: to meet accumulated mutating of SARS-CoV-2 and a long-term viral genome transcrption COVID-19 (Coronavirus Disease 2019) is novel viral pneumonia caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, also called 2019nCoV). The world is in midst of the COVID-19 pandemic. Effective vaccines are […]

Viral vector-based vaccine; DNA-based vaccine; RNA based vaccine- A landscape for vaccine technology against infectious disease, COVID-19 and tumor

COVID-19 vaccine development protocol: PSV Based Neutralization Assay Table of Contents Abstract The vaccine helps to provoke the immune system and is an efficacious means for disease prevention and treatment. At this particular time of the COVID-19 outbreak, the vaccine for COVID-19 is urgently needed to save tens of thousands of people’s lives. Here we […]

Landscape Coronavirus Disease 2019 test (COVID-19 test) in vitro

Full text download Author:Huajun Bai1 Xiaolong Cai1, 2*  Xiaoyan Zhang11. R&D Center, GeneMedi Co.Ltd., Shanghai, P.R. China (www.genemedi.com)2. Hanbio Research Center, Hanbio Tech Co. Ltd., Shanghai, P.R. China (www.hanbio.net) Abstract:The outbreak of COVID-19, caused by 2019 novel coronavirus (2019-nCoV), has been a global public health threat and caught the worldwide concern. Scientists throughout the world are sparing […]

GeneMedi knowledge base of Coronavirus disease 2019 (COVID-19): A Collection of reviews, diagnosis protocols, and guidance

1. Introduction COVID-19, a novel pathogenic coronavirus (2019-nCoV or SARS-CoV2) induced disease, emerged in China and spread globally rapidly. GeneMedi produces kinds of recombinant 2019 nCoV(SARS2 coronavirus) antigens as shown below: Nucleocapsid(N protein), Spike(S protein), RBD, S1+S2 ECD, Envelope (E protein), 3C-like Proteinase. All the recombinant proteins of 2019 nCoV are suitable for in functional […]

An Insight of comparison between COVID-19 (2019-nCoV) and SARS-CoV in pathology and pathogenesis

Full-text Download Author:Xiaolong Cai1. Hanbio Research Center, Hanbio Tech Co. Ltd., Shanghai, P.R. China (www.hanbio.net)2. R&D Center, GeneMedi Co.Ltd., Shanghai, P.R. China (www.genemedi.com) Abstract:COVID-19, a novel pathogenic coronavirus emerged in China and spread globally rapidly. COVID-19 shares above 85% identity in genome with SARS-CoV. Patients infected by COVID-19 and SARS-CoV also reveal similar clinical characteristics. Here […]

CAR-NK immunotherapy and cancer therapy

Lentivirus Protocol Download Cell therapy is a kind of medicine aiming to cure disease or alleviate disease symptoms via direct infusion or transplantation of cells, which can be autologous or allogeneic. With several decades’ development and optimization, immuno-oncology cells (such as T cells, nature killer cells, etc.), stem cells (embryonic stem cells, induced pluripotent stem […]

TCR-T immunotherapy and cancer therapy

Lentivirus Protocol Download Cell therapy is a kind of medicine aiming to cure disease or alleviate disease symptoms via direct infusion or transplantation of cells, which can be autologous or allogeneic. With several decades’ development and optimization, immuno-oncology cells (such as T cells, nature killer cells, etc.), stem cells (embryonic stem cells, induced pluripotent stem […]

CAR-T immunotherapy and cancer therapy

Lentivirus Protocol Download Cell therapy is a kind of medicine aiming to cure disease or alleviate disease symptoms via direct infusion or transplantation of cells, which can be autologous or allogeneic. With several decades’ development and optimization, immuno-oncology cells (such as T cells, nature killer Chimeric antigen receptor (CAR)-modified T cells (CAR-T) are T cells […]