Category Archives: gene therapy

AAV Knowledge base

Adeno-associated virus (AAV) Knowledge base AAV serotypes and AAV Tissue-specific Tropism Over the past decades, numerous AAV serotypes have been identified with variable tropism. Read More Life Cycle of AAV Virus-From Infection To Regeneration AAV establishes latency by undergoing specifically integration into a genome site, termed as the adeno-associated virus integration site 1 (AAVS1), a […]

AAV capsids evolution and tissue-specific AAV discovery & development service

The Genemedi help scientists and researchers in gene therapy vector development. Besides different scales of AAV production, we can also offer novel AAV discovery services with AAV re-engineering capsids library and sub-library generation based on different strategies, customized AAV capsids screening and tissue-specific AAV tropism validation.  1. AAV engineering capsids library and sub-library generation 1) […]

CRISPR/Cas9?system?and Gene editing therapy

CRISPR/Cas9 protocol Download Gene editing, also called genome editing, is a group of technologies to change the sequence of DNA in the genome. Several approaches to genome editing have been developed, including Zinc Finger, TALEN, and CRISPR/Cas9. Compared with the other gene editing tools, CRISPR/Cas9 system is faster, cheaper, more accurate, and more efficient, showing […]

CRISPR/Cas9 system – gRNA design and validation – principle and protocol

CRISPR/Cas9 protocol Download Gene editing, also called genome editing, is a group of technologies to change the sequence of DNA in the genome. Several approaches to genome editing have been developed, including Zinc Finger, TALEN, and CRISPR/Cas9. Compared with the other gene editing tools, CRISPR/Cas9 system is faster, cheaper, more accurate, and more efficient, showing […]

Viral vector-based vaccine; DNA-based vaccine; RNA based vaccine- A landscape for vaccine technology against infectious disease, COVID-19 and tumor

COVID-19 vaccine development protocol: PSV Based Neutralization Assay Table of Contents Abstract The vaccine helps to provoke the immune system and is an efficacious means for disease prevention and treatment. At this particular time of the COVID-19 outbreak, the vaccine for COVID-19 is urgently needed to save tens of thousands of people’s lives. Here we […]

Pre-made control lentiviral vector (lentivirus with vsv-G envelop) particles with fluorescent labels and antibiotics resistance

GeneMedi Lab offer a variety of Pre-made and Pre-packaging control lentiviral vector (lentivirus with vsv-G envelop) particleswith different fluorescent labels (such as GFP, RFP, YFP, luciferase, zsgreen, mCherry and so on), GeneMedi’s lentiviral vector drived by various promoters (such as CMV, CAG, U6, syn, TBG and cTNT etc.) with antibiotics resistance (for example, puromycin resistance). […]

Pre-made control adenovirus vector (ad5) particles with fluorescent labels

GeneMedi Lab offer a variety of Pre-made and Pre-packaging control adenovirus vector (serotype 5 adenoviral vector, Ad5) particleswith different fluorescent labels (such as GFP, RFP, YFP, luciferase, zsgreen, mCherry and so on), GeneMedi’s adenoviral vector system drived by various promoters (such as CMV, CAG, U6, syn, TBG and cTNT etc.). Our ready-to-use control adenovirus vectors […]

Pre-made control AAV vector (adeno-associated virus) particles with fluorescent labels

For customized AAV Control Virus (GFP, RFP, luciferase) Service, please click here>> GeneMedi Lab offer a variety of Pre-made and Pre-packaging control AAV vector (adeno-associated virus) particles in multiple AAV serotypes (AAV2, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-Retro, AAV-PHP, AAV2.7M8, AAVRh10 and so on) with different fluorescent labels (such as GFP, RFP, YFP, luciferase, zsgreen, […]

Optogenetics Adeno Associated Virus (AAV) premade products

Introduction to Optogenetics Adeno Associated Virus (AAV) Products For customized AAV Optogenetics Production Service, please click here>> OptogeneticsOptogenetics has been a powerful scientific tool to further the fundamental scientific understanding of how specific cell types contribute to the function of biological tissues, such as neural circuits in vivo and lead to new insights into Parkinson’s […]