Category Archives: gene therapy

Adenovirus Control Prodcution

Introduction to Adenovirus Control Prodcution Recombinant adenovirus (Adenovirus), a replication-defective adenoviral vector system, is widely used for gene delivery in most cell types. The adenoviral vectors provided by Genemedi are based on human adenovirus type 5 (Ad5), which is replication-incompetent (-E1/-E3) and can’t be integrated into host genome, guaranteeing the security for subsequent operations. Adenovirus […]

Viral vector-based vaccine; DNA-based vaccine; RNA based vaccine – A landscape for vaccine technology against infectious disease, COVID-19 and tumor.

COVID-19 vaccine development protocol: PSV Based Neutralization Assay DNA based vaccines Traditionally, vaccines are prepared with killed or attenuated viruses or bacteria, which might have serious security issues for the development of HIV vaccines. Additionally, vector-based vaccines may induce anti-vector immunity, which might interfere the immune responses provoked by vaccines [113]. Thus, DNA vaccines were […]

 Inducible-tissue specific Cre-loxP system for in vivo and in vitro study

View Knowledge Base – Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre)>> Product list: Cre/loxP tools in AAV vector(AAV-Cre), adenoviral vector(Ad-Cre) and lentiviral vector(Lv-Cre) Abstract Cre-loxP system is widely used in the field of biosciences, especially in the generation of genetically engineered mice (knockout or overexpression), enabling researchers to study […]

Pre-made Adenovirus Production And Pre-made Adenovirus particle)

Begin your customized ADV production process Introduction to Pre-made Adenovirus Production And Pre-made Adenovirus particle) Besides various adenoviral expression systems used for altering gene expression or monitoring gene expression, more than 10 thousand adenoviral ORF plasmids, which have been confirmed by sequencing, are available for direct Adv packaging. The adenoviral vectors provided by Genemedi are based on […]

Adeno Associated Virus (AAV) Expression Vector (AAV expression plasmids)

AAV protocol Download AAV User Manual Download Adeno Associated Virus (AAV) Expression Vector (AAV expression plasmids) – Introduction GeneMedi’s AAV expression vector also named AAV expression plasmid, is part of AAV packaging system. GeneMedi’s AAV expression vectors have been inserted with differernt expression cassettes, containing kinds of verified protomters and reporters including GFP,zsgreen, RFP, mcherry […]

Potency validation of GeneMedi’s P24 antibody pairs in lentivirus-titration using sandwich ELISA

Lentiviral vectors are efficient vehicles for stable gene transfer in both dividing and non-dividing cells. This feature among others makes lentiviral vectors a powerful tool in molecular research. However, the use of lentiviruses in research studies and clinical trials requires a precise and validated titration method. Application development scientists of GDU (GeneMedi Diagnostics Unit) have […]

Lentivirus vector system (lentivirus expression system, lentivirus packaging plasmid system)

Lentivirus protocol Download Lentivirus User Manual Download Lentivirus vector system – Introduction GeneMedi’s lentivirus Vector System, also named the lentivirus expression system or lentivirus packaging plasmid system, is a powerful tool for in-vitro & in-vivo gene delivery, shRNA mediated RNA interference (RNAi), gene editing and stable cellline development. You can easily produce a recombinant lentivirus particle in HEK293T or HEK293FT […]

Introduction of animal infectious disease

View Knowledge Base – Validated animal health diagnostic antibodies pairs and antigens for animal infectious diseases diagnostic testing in ELISA, Lateral flow immunoassay (LFIA) and other immunoassays >> Abstract – Animal health diagnosis Animal infectious diseases pose a continuing threat to animal health, food safety, national economy, and the environment. Zoonotic infections, also named as […]

Introduction of Cre-loxP system |-GeneMedi

View Knowledge Base – Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre)>> Product list: Cre/loxP tools in AAV vector(AAV-Cre), adenoviral vector(Ad-Cre) and lentiviral vector(Lv-Cre) Abstract Cre-loxP system is widely used in the field of biosciences, especially in the generation of genetically engineered mice (knockout or overexpression), enabling researchers to study […]

AAV-DIO in neuroscience |-GeneMedi

AAV-DIO in neuroscience View Knowledge Base – Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre)>> Product list: Cre/loxP tools in AAV vector(AAV-Cre), adenoviral vector(Ad-Cre) and lentiviral vector(Lv-Cre) Cat No. Pre-made Cre Viral vector Protomer Promoter Tissue Specificity Promoter Tissue Specificity characteristics GMV-AdCre-01 Ad-CMV-Cre Adenovirus CMV Total Total GMV-AdCre-02 Ad-CMV-Cre-GFP CMV […]