Fibrinogen disorders are a set of hereditary or acquired abnormalities in the quantity and/or quality of circulating fibrinogens. The disorders may lead to pathological bleeding and/or blood clotting or the deposition of fibrinogen in the liver, kidneys, or other organs and tissues. These disorders include Congenital afibrinogenemia, Congenital hypofibrinogenemia, Fibrinogen storage disease, Congenital dysfibrinogenemia, Hereditary fibrinogen Aα-Chain amyloidosis, Acquired dysfibrinogenemia, Congenital hypo dysfibrinogenemia and Cryofibrinogenemia. The detection of fibrinogen and so on are used to diagnose the fibrinogen disorders. However, the detection of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.