human ROR1 Lentivirus plasmid

Cat:pGMLV000229
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLV000229

Gene Name

ROR1

Product Name

human ROR1 Lentivirus plasmid

Accession Number

NM_005012

Gene ID

4919

Species

human

Product Type

Lentivirus plasmid

Insert Length

2814

Gene Alias

dJ537F10.1;NTRKR1

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

Maker

GFP+PURO

Regulation

overexpression