Norway rat Me2 Lentivirus plasmid
Cat:pGMLV000676
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000676
Gene Name
Me2
Product Name
Norway rat Me2 Lentivirus plasmid
Accession Number
NM_001107376.2
Gene ID
307270
Species
Norway rat
Product Type
Lentivirus plasmid
Insert Length
1755
Gene Alias
Predicted to enable malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process; pyruvate metabolic process; and regulation of NADP metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in mitochondrion. Orthologous to human ME2 (malic enzyme 2). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]
Maker
GFP+PURO
Regulation
overexpression
