house mouse Sirt3 AAV plasmid
Cat:pGMAAV000256
Availability:3-7 business days
Description
Catalog ID
pGMAAV000256
Gene Name
Sirt3
Product Name
house mouse Sirt3 AAV plasmid
Accession Number
NM_001177804.1
Gene ID
64384
Species
house mouse
Product Type
AAV plasmid
Insert Length
1005
Gene Alias
Sir2l3; 2310003L23Rik
Fluorescent Label
ZsGreen
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
Maker
Regulation
overexpression
