Norway rat Fyn AAV plasmid
Cat:pGMAAV000262
Availability:3-7 business days
Description
Catalog ID
pGMAAV000262
Gene Name
Fyn
Product Name
Norway rat Fyn AAV plasmid
Accession Number
NM_012755.1
Gene ID
25150
Species
Norway rat
Product Type
AAV plasmid
Insert Length
1614
Gene Alias
Enables several functions, including phosphatidylinositol 3-kinase binding activity; protein tyrosine kinase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to organonitrogen compound; negative regulation of cell death; and protein phosphorylation. Located in several cellular components, including mitochondrion; perinuclear endoplasmic reticulum; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Alzheimer’s disease and schizophrenia. Orthologous to human FYN (FYN proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
ZsGreen
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]
Maker
Regulation
overexpression
