Cat:pGMAD000513
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMAD000513
Gene Name
Wdr6
Product Name
Accession Number
NM_031392.2
Gene ID
83669
Species
house mouse
Product Type
Adenovirus plasmid
Insert Length
3378
Gene Alias
Predicted to enable insulin receptor substrate binding activity. Predicted to be involved in several processes, including negative regulation of autophagy; negative regulation of cell population proliferation; and tRNA methylation. Predicted to be located in cytosol and plasma membrane. Predicted to be part of COP9 signalosome. Predicted to be active in cytoplasm. Is expressed in central nervous system; nervous system; neural retinal epithelium; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human WDR6 (WD repeat domain 6). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Maker
GFP
Regulation
overexpression
