Cat:pGMAD000544
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMAD000544 Categories , , ,

Availability:3-7 business days

Description

Catalog ID

pGMAD000544

Gene Name

AXL

Product Name

Accession Number

NM_021913.5

Gene ID

558

Species

human

Product Type

Adenovirus plasmid

Insert Length

2685

Gene Alias

ARK;JTK11;Tyro7;UFO

Fluorescent Label

EGFP

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]

Maker

EGFP

Regulation

overexpression