Cat:pGMAD000603
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMAD000603
Gene Name
Hdac1
Product Name
Accession Number
NM_001025409.1
Gene ID
297893
Species
Norway rat
Product Type
Adenovirus plasmid
Insert Length
1449
Gene Alias
Enables DNA-binding transcription factor binding activity; chromatin binding activity; and histone deacetylase activity. Involved in several processes, including positive regulation of cytokine production; regulation of apoptotic process; and regulation of protein modification process. Located in several cellular components, including chromatin; neuron projection; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of pulmonary hypertension. Orthologous to human HDAC1 (histone deacetylase 1). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Maker
GFP
Regulation
overexpression
