Cat:pGMAD000656
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU
pGMAD000656
Categories adv, ADV plasmid, Gene Therapy, orf
Availability:3-7 business days
Description
Catalog ID
pGMAD000656
Gene Name
Cidec
Product Name
Accession Number
NM_001024333.2
Gene ID
500292
Species
Norway rat
Product Type
Adenovirus plasmid
Insert Length
747
Gene Alias
Predicted to be involved in execution phase of apoptosis; lipid droplet organization; and regulation of apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 5. Orthologous to human CIDEC (cell death inducing DFFA like effector c). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Maker
GFP
Regulation
overexpression