rat Cxcr4 Lentivirus plasmid
Cat:pGMLV000065
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000065
Gene Name
Cxcr4
Product Name
rat Cxcr4 Lentivirus plasmid
Accession Number
NM_022205.3
Gene ID
60628
Species
rat
Product Type
Lentivirus plasmid
Insert Length
1050
Gene Alias
Enables small molecule binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; endothelium development; and nervous system development. Located in endosome; nucleus; and plasma membrane. Used to study pulmonary hypertension and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in WHIM syndrome; hematologic cancer (multiple); leukopenia; osteoporosis; and pancreatic adenocarcinoma. Orthologous to human CXCR4 (C-X-C motif chemokine receptor 4). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP+PURO
Fusion Tag
NULL
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Maker
GFP+PURO
Regulation
overexpression
