mouse Hoxb13 Lentivirus plasmid

Cat:pGMLV000165
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLV000165

Gene Name

Hoxb13

Product Name

mouse Hoxb13 Lentivirus plasmid

Accession Number

NM_008267.3

Gene ID

15408

Species

mouse

Product Type

Lentivirus plasmid

Insert Length

861

Gene Alias

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and methyl-CpG binding activity. Acts upstream of or within epithelial cell maturation involved in prostate gland development; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; and regulation of growth. Part of transcription regulator complex. Is expressed in several structures, including genitourinary system; gut; lung; spinal cord; and tail. Human ortholog(s) of this gene implicated in ductal carcinoma in situ and renal cell carcinoma. Orthologous to human HOXB13 (homeobox B13). [provided by Alliance of Genome Resources, Apr 2022]

Fluorescent Label

RFP

Fusion Tag

no tag

Promoter

CMV

Resistance

Amplicin

gene description

This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]

Maker

RFP

Regulation

overexpression