human POU5F1 Lentivirus plasmid
Cat:pGMLV000277
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000277
Gene Name
POU5F1
Product Name
human POU5F1 Lentivirus plasmid
Accession Number
NM_002701.4
Gene ID
5460
Species
human
Product Type
Lentivirus plasmid
Insert Length
1083
Gene Alias
Oct-3;Oct-4;OCT3;OCT4;OTF-3;OTF3;OTF4
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing’s sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
Maker
GFP+PURO
Regulation
overexpression
