human CASR Lentivirus plasmid
Cat:pGMLV000369
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000369
Gene Name
CASR
Product Name
human CASR Lentivirus plasmid
Accession Number
NM_001178065
Gene ID
846
Species
human
Product Type
Lentivirus plasmid
Insert Length
3267
Gene Alias
CAR;EIG8;FHH;FIH;GPRC2A;hCasR;HHC;HHC1;HYPOC1;NSHPT;PCAR1
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
Maker
GFP+PURO
Regulation
overexpression
