human EGFR Lentivirus plasmid

Cat:pGMLV000508
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLV000508 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLV000508

Gene Name

EGFR

Product Name

human EGFR Lentivirus plasmid

Accession Number

NM_005228.4

Gene ID

1956

Species

human

Product Type

Lentivirus plasmid

Insert Length

3633

Gene Alias

ERBB;ERBB1;HER1;mENA;NISBD2;PIG61

Fluorescent Label

PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]

Maker

PURO

Regulation

overexpression