human YWHAE Lentivirus plasmid

Cat:pGMLV000631
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLV000631

Gene Name

YWHAE

Product Name

human YWHAE Lentivirus plasmid

Accession Number

NM_006761

Gene ID

7531

Species

human

Product Type

Lentivirus plasmid

Insert Length

768

Gene Alias

14-3-3E;HEL2;KCIP-1;MDCR;MDS

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

Maker

GFP+PURO

Regulation

overexpression