Norway rat Mgat5 Lentivirus plasmid
Cat:pGMLV000780
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000780
Gene Name
Mgat5
Product Name
Norway rat Mgat5 Lentivirus plasmid
Accession Number
NM_023095.1
Gene ID
65271
Species
Norway rat
Product Type
Lentivirus plasmid
Insert Length
2223
Gene Alias
Predicted to enable alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; manganese ion binding activity; and protein phosphatase inhibitor activity. Predicted to be involved in several processes, including negative regulation of protein tyrosine phosphatase activity; positive regulation of receptor signaling pathway via STAT; and protein N-linked glycosylation via asparagine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Used to study proteinuria. Orthologous to human MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP-PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
Maker
GFP-PURO
Regulation
overexpression
