human RUNX1 Lentivirus plasmid

Cat:pGMLV000843
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLV000843 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLV000843

Gene Name

RUNX1

Product Name

human RUNX1 Lentivirus plasmid

Accession Number

NM_001754

Gene ID

861

Species

human

Product Type

Lentivirus plasmid

Insert Length

1443

Gene Alias

AML1;AML1-EVI-1;AMLCR1;CBF2alpha;CBFA2;EVI-1;PEBP2aB;PEBP2alpha

Fluorescent Label

GFP-PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Maker

GFP-PURO

Regulation

overexpression