human ATG10 Lentivirus plasmid

Cat:pGMLP000172
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLP000172 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLP000172

Gene Name

ATG10

Product Name

human ATG10 Lentivirus plasmid

Accession Number

NM_031482

Gene ID

83734

Species

human

Product Type

Lentivirus plasmid

Insert Length

663

Gene Alias

APG10;APG10L;pp12616

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]

Maker

GFP+PURO

Regulation

overexpression