Diagnostic recombinant pepsinogen I (PG I) antigens (recombinant pepsinogen I (PG I) ) protein) for gastric disease PG I detection in positive control, ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Product Details
There are two main types of pepsinogen (PG), namely PG I (PG A) and PG II (PG C). Both of these types are produced in the essential cells in the stomach corpus and fundus and in mucous cervical cells. Unlike PG A, PG C is also produced in the Brunner glands in the proximal duodenum and in the pyloric glands in the antrum [8]. Serum pepsinogen levels reflect the morphological and functional status of the stomach mucosa, so they serve as markers of chronic atrophic gastritis [9]. Low levels of serum PG A and PG A / PG C are observed in patients with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer [8].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261308/ Genemedi produces core diagnostic ingredients for test of gastric disease and related syndrome. GeneMedi offers paired diagnostics grade pepsinogen I (PG I) antibodies (monoclonal antibody, mab) and pepsinogen I (PG I) antigens for gastric disease rapid test kit of pepsinogen I (PG I) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.All the antibodies and antigens for gastric disease test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibodies can act as a capture antibody and detection antibody. The antigens can be used for antibodies rapid test of gastric disease.
Product Description
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Antigen & Antibody Name
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Expression platform
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Isotypes
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Bioactivity validation
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Tag
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Products description
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Purity
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Application
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Formulation
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Storage
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Cat No.
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GMP-PG-I-Ag
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Product Name
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Recombinant human Human PG I Protein
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Expression platform
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E.coli
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Isotypes
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Recombinant Antigen
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Bioactivity validation
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pepsinogen I (PG I) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of Gastric disease (atrophic gastritis,
pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and
gastric cancer) and related syndrome evaluation
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Tag
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His
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Products description
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Recombinant human Human PG I Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
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Purity
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Purity: ≥95% (SDS-PAGE)
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Application
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Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
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Formulation
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Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
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Storage
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Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Diagnostic antibodies and antigens for infectious disease testing including HIV/AIDS, HCV, Influenza A/B, Syphilis, Helicobacter pylori, HSV-1/2, CMV, rubella virus, toxoplasma.
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction.
Genemedi produces core diagnostic ingredients for test of infectious diseases and related syndrome.
GeneMedi offers paired diagnostics grade antibodies (monoclonal antibody,mab)and antigens for infectious disease rapid test kit including infection of HIV/AIDS,Hepatitis C virus(HCV), Influenza A/B,Treponema Pallidum caused Syphilis,Helicobacter pylori (H. pylori) Bacteria, Herpes simplex virus 1/2(HSV-1/HSV-2),Cytomegalovirus (CMV),rubella virus,toxoplasma gondii and so on.
All the antibodies of inflammation and CRS test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibody can act as a capture antibody and detection antibody.
