Pre-made Cobolimab benchmark antibody ( Whole mAb, anti-HAVCR2/TIM3 therapeutic antibody, Anti-CD366/KIM-3/SPTCL/TIMD3/Tim-3/TIMD-3/HAVcr-2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-113

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SKU GMP-Bios-ab-113 Category Tag

Product Details

Pre-Made Cobolimab biosimilar, Whole mAb, Anti-HAVCR2/TIM3 Antibody: Anti-CD366/KIM-3/SPTCL/TIMD3/Tim-3/TIMD-3/HAVcr-2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Products Name (INN Index)

Pre-Made Cobolimab biosimilar, Whole mAb, Anti-HAVCR2/TIM3 Antibody: Anti-CD366/KIM-3/SPTCL/TIMD3/Tim-3/TIMD-3/HAVcr-2 therapeutic antibody

INN Name

Cobolimab

Target

HAVCR2

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG4

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-II/III

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2018

Companies

AnaptysBio,GlaxoSmithKline,TESARO

Conditions Approved

NA

Conditions Active

Non-small cell lung cancer,Liver cancer,Malignant Melanoma

Conditions Discontinued

Solid tumours

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

HAVCR2/TIM3

Package

, ,

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