Pre-made Naptumomab benchmark antibody ( Fab Fusion, anti-TPBG therapeutic antibody, Anti-5T4/M6P1/5T4AG/WAIF1 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Naptumomab biosimilar, Fab Fusion, Anti-TPBG Antibody: Anti-5T4/M6P1/5T4AG/WAIF1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Naptumomab estafenatox (ABR-217620) is a drug being developed for the treatment of various types of cancer like non-small cell lung carcinoma and renal cell carcinoma.
| Products Name (INN Index) | Pre-Made Naptumomab biosimilar, Fab Fusion, Anti-TPBG Antibody: Anti-5T4/M6P1/5T4AG/WAIF1 therapeutic antibody |
|---|---|
| INN Name | Naptumomab |
| Target | TPBG |
| Format | Fab Fusion |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2006 |
| Year Recommended | 2007 |
| Companies | Active Biotech |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Non-small cell lung cancer,Pancreatic cancer,Renal cancer |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | TPBG |
| Package |
