Pre-made Narnatumab benchmark antibody ( Whole mAb, anti-MST1R/RON therapeutic antibody, Anti-RON/SEA/PTK8/CD136/NPCA3/CDw136 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Narnatumab biosimilar, Whole mAb, Anti-MST1R/RON Antibody: Anti-RON/SEA/PTK8/CD136/NPCA3/CDw136 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Narnatumab is a human monoclonal antibody designed for the treatment of cancer.[1] Clinical development was abandoned after phase I trials.
| Products Name (INN Index) | Pre-Made Narnatumab biosimilar, Whole mAb, Anti-MST1R/RON Antibody: Anti-RON/SEA/PTK8/CD136/NPCA3/CDw136 therapeutic antibody |
|---|---|
| INN Name | Narnatumab |
| Target | MST1R |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2011 |
| Year Recommended | 2012 |
| Companies | ImClone Systems,Eli Lilly,ImClone Systems |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Solid tumours |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | MST1R |
| Package |
