Pre-made Ozanezumab benchmark antibody ( Whole mAb, anti-RTN4 therapeutic antibody, Anti-ASY/NI220/250/NOGO/NSP/NSP-CL/Nbla00271/Nbla10545/RTN-X-B1-B2 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Ozanezumab biosimilar, Whole mAb, Anti-RTN4 Antibody: Anti-ASY/NI220/250/NOGO/NSP/NSP-CL/Nbla00271/Nbla10545/RTN-X-B1-B2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Ozanezumab is a monoclonal antibody designed for the treatment of ALS and multiple sclerosis.
| Products Name (INN Index) | Pre-Made Ozanezumab biosimilar, Whole mAb, Anti-RTN4 Antibody: Anti-ASY/NI220/250/NOGO/NSP/NSP-CL/Nbla00271/Nbla10545/RTN-X-B1-B2 therapeutic antibody |
|---|---|
| INN Name | Ozanezumab |
| Target | RTN4 |
| Format | Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2012 |
| Year Recommended | 2013 |
| Companies | GlaxoSmithKline |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Amyotrophic lateral sclerosis,Multiple sclerosis |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | RTN4 |
| Package |
