Pre-made Pateclizumab benchmark antibody ( Whole mAb, anti-LTA therapeutic antibody, Anti-LT/TNFB/TNFSF1/TNLG1E Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-430

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SKU GMP-Bios-ab-430 Category Tag

Product Details

Pre-Made Pateclizumab biosimilar, Whole mAb, Anti-LTA Antibody: Anti-LT/TNFB/TNFSF1/TNLG1E therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Pateclizumab (MLTA3698A) is an immunomodulator. It binds to lymphotoxin alpha.

Products Name (INN Index)

Pre-Made Pateclizumab biosimilar, Whole mAb, Anti-LTA Antibody: Anti-LT/TNFB/TNFSF1/TNLG1E therapeutic antibody

INN Name

Pateclizumab

Target

LTA

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Discontinued

100% SI Structure

4mxv:HL:YX:FE/4mxw:HL:WV

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2011

Companies

Genentech

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

Rheumatoid arthritis

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

LTA

Package

, ,

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