Pre-made Risankizumab benchmark antibody ( Whole mAb, anti-IL23A/IL23 therapeutic antibody, Anti-IL23P19/P19/SGRF Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-486

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SKU GMP-Bios-ab-486 Category Tag

Product Details

Pre-Made Risankizumab biosimilar, Whole mAb, Anti-IL23A/IL23 Antibody: Anti-IL23P19/P19/SGRF therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Risankizumab, sold under the brand name Skyrizi, is a humanized monoclonal antibody targeting interleukin 23A (IL-23A). Risankizumab is part of a collaboration between Boehringer Ingelheim and AbbVie. Risankizumab has been approved in the European Union,[4] the United States, Canada, and Japan for treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy.

Products Name (INN Index)

Pre-Made Risankizumab biosimilar, Whole mAb, Anti-IL23A/IL23 Antibody: Anti-IL23P19/P19/SGRF therapeutic antibody

INN Name

Risankizumab

Target

IL23A

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2015

Companies

AbbVie,Boehringer Ingelheim

Conditions Approved

Erythrodermic psoriasis,Plaque psoriasis,Psoriatic arthritis,Pustular psoriasis

Conditions Active

Crohn's disease,Ulcerative colitis,Atopic dermatitis

Conditions Discontinued

Psoriasis,Ankylosing spondylitis,Asthma

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

IL23A

Package

, ,

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