Pre-made Vesencumab benchmark antibody ( Whole mAb, anti-NRP1 therapeutic antibody, Anti-BDCA4/CD304/NP1/NRP/VEGF165R Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Vesencumab biosimilar, Whole mAb, Anti-NRP1 Antibody: Anti-BDCA4/CD304/NP1/NRP/VEGF165R therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Roche and Genentech are developing vesencumab, a human IgG1 monoclonal antibody that targets neuropilin 1 (NRP1), for the treatment of solid tumours.
| Products Name (INN Index) | Pre-Made Vesencumab biosimilar, Whole mAb, Anti-NRP1 Antibody: Anti-BDCA4/CD304/NP1/NRP/VEGF165R therapeutic antibody |
|---|---|
| INN Name | Vesencumab |
| Target | NRP1 |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Discontinued |
| 100% SI Structure | 2qqn:HL |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2010 |
| Year Recommended | 2011 |
| Companies | Genentech,Roche |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Solid tumours |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | NRP1 |
| Package |
