Pre-made Capromab benchmark antibody (Radiolabelled antibody, anti-FOLH1/GCPII therapeutic antibody, Anti-FGCP/FOLH/GCP2/NAALAD1/PSM/PSMA/mGCP Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-made Capromab benchmark antibody (Radiolabelled antibody, anti-FOLH1/GCPII therapeutic antibody, Anti-FGCP/FOLH/GCP2/NAALAD1/PSM/PSMA/mGCP Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer.[1] Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA.[2] Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single-photon emission computed tomography (SPECT).[1]
| Products Name (INN Index) | Pre-Made Capromab Biosimilar, Radiolabelled Antibody, Anti-FOLH1/GCPII Antibody: Anti-FGCP/FOLH/GCP2/NAALAD1/PSM/PSMA/mGCP therapeutic antibody |
|---|---|
| INN Name | capromab |
| Target | FOLH1 |
| Format | Radiolabelled antibody |
| Derivation | Mus musculus |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 – kappa |
| VD LC | IgG1 – kappa |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | EUSA?Pharma (Doylestown PA USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | FOLH1 |
| Package |
