Pre-Made Interferon Alfa Biosimilar, Recombinant Protein targeting IFNAR1: Recombinant therapeutic protein targeting AVP/IFN-alpha-REC/IFNAR/IFNBR/IFRC for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-INN-871

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SKU GMP-Bios-INN-871 Category Tag

Product Details

Pre-Made Interferon Alfa Biosimilar, Recombinant Protein targeting IFNAR1: Recombinant therapeutic protein targeting AVP/IFN-alpha-REC/IFNAR/IFNBR/IFRC is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-¦Á), obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-¦Á subtypes and is purified by affinity chromatography. Although the pharmaceutical product is often simply called “interferon alpha” or “IFN-¦Á” like its endogenous counterpart, the product’s International nonproprietary name (INN) is interferon alfa (the spelling of ‘alfa’ with ‘f’ reflects INN naming conventions).

Interferon alfa is an immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma.

Products Name (INN Index)

Pre-Made Interferon Alfa Biosimilar, Recombinant Protein targeting IFNAR1: Recombinant therapeutic protein targeting AVP/IFN-alpha-REC/IFNAR/IFNBR/IFRC

INN Name

interferon alfa

Target

IFNAR1

Format

Recombinant Protein

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IFNA2 (interferon alpha 2) *a (K56,H57) 24-188

VD LC

IFNA2 (interferon alpha 2) *a (K56,H57) 24-188

Highest_Clin_Trial (Jan '20)

NA

Est. Status

NA

100% SI Structure

NA

99% SI Structure

NA

95-98% SI Structure

NA

Year Proposed

NA

Companies

Roche,?F. Hoffmann-La?Roche Ltd. (Basel Switzerland)

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

IFNAR1

Package

, ,

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