Pre-Made Somatropin Biosimilar, Recombinant Protein targeting GHR: Recombinant therapeutic protein targeting GHBP/GHIP for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Somatropin Biosimilar, Recombinant Protein targeting GHR: Recombinant therapeutic protein targeting GHBP/GHIP is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication¡ªit is one form of hormone therapy. Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical controversies for 5 years.
Somatotropin is a recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
| Products Name (INN Index) | Pre-Made Somatropin Biosimilar, Recombinant Protein targeting GHR: Recombinant therapeutic protein targeting GHBP/GHIP |
|---|---|
| INN Name | somatropin |
| Target | GHR |
| Format | Recombinant Protein |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | GH1 (growth hormone 1, somatotropin, GH, GH-N, GHN, hGH- N, pituitary growth hormone) |
| VD LC | GH1 (growth hormone 1, somatotropin, GH, GH-N, GHN, hGH- N, pituitary growth hormone) |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Genentech?Inc. (S. San Francisco CA USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | GHR |
| Package |
