GMP-BioFcR-ag-049
$5,990.00 – $293,000.00
Human Fc epsilon receptor II (FcεRII, CD23) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies.
GeneMedi provides Human Fc epsilon receptor II (FcεRII, CD23) His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgE. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
| Products Name1 | GMP-BioFcR-ag-049-1:Human Fc epsilon receptor II (FcεRII, CD23) His+Avi |
|---|---|
| Products Name2 | GMP-BioFcR-ag-049-2:Human Fc epsilon receptor II (FcεRII, CD23) His+Avi (Biotinylated) |
| Isotype | Fc epsilon receptor II (FcεRII, CD23) |
| Receptor name | |
| Species | Human |
| Principal antibody ligand | IgE |
| Major role | IgE regulation |
| Effect following binding to antibody | Possible adhesion molecule, IgE transport across human intestinal epithelium, Positive-feedback mechanism to enhance allergic sensitization (B cells) |
| WT/Mutation | WT |
| Mutant variants functions vs WT | N/A |
| Application | Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, Biacore-based SRP assay or BLI assay) |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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