Cat:GMP-h-MMP3
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Product Details

Genemedi produces core diagnostic ingredients for test of Cardiovascular disease (cancer, asthma and rheumatoid arthritis) and related syndrome. GeneMedi offers paired diagnostics grade matrix metalloproteinase-3 (MMP3) antibodies (monoclonal antibody, mab) and antigens for Cardiovascular disease (cancer, asthma and rheumatoid arthritis) rapid test kit of matrix metalloproteinase-3 (MMP3) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Cardiovascular disease (cancer, asthma and rheumatoid arthritis ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Matrix metalloproteinases (MMPs) are a large family of proteases involved in many cell-matrix and cell-cell signalling processes through activation, inactivation or release of extracellular matrix (ECM) and non-ECM molecules, such as growth factors and receptors. Uncontrolled MMP activities underlie the pathophysiology of many disorders. Also, matrix metalloproteinase-3 (MMP-3) or stromelysin-1 contributes to several pathologies, such as cancer, asthma and rheumatoid arthritis, and has also been associated with neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease and multiple sclerosis.

Product Description

Cat No. of Pruducts

GMP-h-MMP3-Ag01:Recombinant Human MMP3 Protein

Product Name

Recombinant Human MMP3 Protein

Target

matrix metalloproteinase-3

Alias of Target/Biomarker

CHDS6, MMP-3, SL-1, STMY, STMY1, STR1

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

matrix metalloproteinase-3 (MMP3) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MMP3 level test of Cardiovascular disease (cancer, asthma and rheumatoid arthritis) and related syndrome evaluation

Tag

His

Products description

Recombinant Human MMP3 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-MMP3-Ab01,GMP-h-MMP3-Ab02:Anti-Human MMP3 mouse monoclonal antibody (mAb)

Product Name

Anti-Human MMP3 mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

CHDS6, MMP-3, SL-1, STMY, STMY1, STR1

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human matrix metalloproteinase-3 (MMP3) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other matrix metalloproteinase-3 (MMP3) antibodies in MMP3 level test of Cardiovascular disease (cancer, asthma and rheumatoid arthritis) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human MMP3 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other matrix metalloproteinase-3 (MMP3) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.