Cat:GMP-h-sFlt-1
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Product Details

Genemedi produces core diagnostic ingredients for test of Cancer (ascular diseases and cancer) and related syndrome. GeneMedi offers paired diagnostics grade soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies (monoclonal antibody, mab) and antigens for Cancer (ascular diseases and cancer) rapid test kit of soluble vascular endothelial growth factor receptor-1 (sFlt-1) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Cancer (ascular diseases and cancer ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Formation of new capillary blood vessels from existing microvessels is called Angiogenesis, which plays a fundamental role in many physiological and pathological processes such as embryo genesis, wound healing and cancer. Angiogenic processes are controlled by a multitude of positive and negative regulators. Vascular endothelial growth factor (VEGF) strongly promotes angiogenesis. VEGF exerts multiple reactions by activating cell membrane receptors with tyrosine kinase activity, such as VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1) and VEGFR-3 (Flt-4) (4). The soluble form of the FLT-1 receptor, sFLT-1, is one of the efficient inhibitors of angiogenesis (10,12). The sFLT-1 inhibits VEGF-driven migration of cancer cells. ?VEGF or sFLT-1 genes or their products have been involved in the therapy of vascular diseases and cancer.

Product Description

Cat No. of Pruducts

GMP-h-sFlt-1-Ag01:Recombinant Human sFlt-1 Protein

Product Name

Recombinant Human sFlt-1 Protein

Target

soluble vascular endothelial growth factor receptor-1

Alias of Target/Biomarker

#N/A

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation

Tag

His

Products description

Recombinant Human sFlt-1 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-sFlt-1-Ab01,GMP-h-sFlt-1-Ab02:Anti-Human sFlt-1 mouse monoclonal antibody (mAb)

Product Name

Anti-Human sFlt-1 mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

#N/A

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human soluble vascular endothelial growth factor receptor-2 (sFlt-1) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other soluble vascular endothelial growth factor receptor-2 (sFlt-1) antibodies in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human sFlt-1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other soluble vascular endothelial growth factor receptor-2 (sFlt-1) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.