Anti-PDE4D/ ACRDYS2/ DPDE3 antibody for FACS & in-vivo assay| GMab

Pre-made anti-PDE4D benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PDE4D mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: PDE4D, gene name: PDE4D, also named as ACRDYS2, DPDE3, HSPDE4D, PDE43N2, STRK1, PDE4D. This gene encodes one of four mammalian counterparts to the fruit fly ‘dunce’ gene. The encoded protein has 3′,5′-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009].